Italian cyclist Riccardo Ricco has lost an appeal against his 12-year ban from the sport, the Court of Arbitration for Sport (CAS) said.
The 29-year-old was banned by the Italian Olympic Committee Anti-Doping Agency in April after being found guilty of blood doping.
He had been admitted to hospital in February 2011 after transfusing his own blood, an act which doctors said nearly killed him.
Ricco appealed the ban, arguing the CONI tribunal was not impartial and the proceedings were flawed.
However CAS, sport’s highest tribunal, rejected his case.
Ricco was kicked off the 2008 Tour de France while in second place after failing a test for the blood-booster CERA.