Alan Mario Sant has been appointed by UEFA to control a Champions League match in Luxembourg, on Tuesday.
Sant will be assisted by Ed-ward Spiteri and Chris Francalanza for the tie between Dudelange and SP Tre Penne, of San Marino. The fourth official will be Malcolm Spiteri.
Other Maltese referees in UEFA club competitions this week will be Chris Lautier and Clayton Pisani, both in the Europa League.
Lautier and his team of Mariano Debono, Thomas Debono and Trustin Farrugia Cann, will be in charge of the match between KuPS Kuopio (Finland) and Llanelli (Wales).
Pisani will control the match between Eschen-Mauren (Liechtenstein) and Hafnarfjordur (Iceland).
In Vaduz, the assistant refs for the first qualifying round match will be Ingmar Spiteri and William Debattista and Mario Apap fourth official.