Updted 7.15pm
A motorcyclist and pillion rider were on Wednesday rushed to Mater Dei Hospital following a four-vehicle crash in a Santa Venera tunnel during rush hour.
The police said the crash was reported at around 5.20pm on the southbound lanes of Regional Road.
The lanes were temporarily closed to traffic, with a tailback being reported as far back as Gżira. One lane was reopened by 6pm, while both lanes were reopened by 7.15pm
A police spokesperson said a Range Rover driven by a 43-year-old man from Swieqi, a BMW 320 driven by an 18-year-old man from Swieqi and a motorcycle driven by a 23-year-old man from Mosta were involved in the crash.
Another 23-year-old man also from Mosta was a passenger on the bike.
Upon impact, the bike hit a Mazda Demio driven by a 29-year-old man from Żejtun.
The two men from Mosta were rushed to hospital. By 7.15pm, their condition was as yet uknown, however, they were not in danger of dying.