All eyes are once again on Cristiano Ronaldo as Manchester United aim make amends for a shock Champions League defeat to Young Boys when the Premier League leaders head to West Ham on Sunday.
Second-placed Chelsea are behind United only on goals scored and will look to extend their unbeaten start in a London derby at Tottenham.
Liverpool and Manchester City will not expect to be troubled when Crystal Palace and Southampton visit Anfield and the Etihad respectively on Saturday.
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