A 21-year-old woman from Mellieħa was injured on Monday afternoon when her Peugeot 207 car was involved in a collision with a trailer-truck.
The accident happened on the Mistra bridge which carries the road from Xemxija to Mellieħa.
The south-bound lane was closed for some time but has now reopened, police said.
The woman’s medical condition was not immediately known.
The trailer was being driven by a 48-year-old man from Birzebbuga.