Traffic through Triq Manwel Dimech and the Qormi junction will be barred from tonight as Transport Malta carries out asphalt works.
The road will be completely closed to traffic, including public transport between 8pm (on Friday) and 5.30am.
Drivers are advised to avoid the area and use alternative routes.
This is part of the extensive road works in the area.
Officials will be on site to assist in the traffic management.