Edinson Cavani scored his 52nd goal for Uruguay on Thursday in a 2-0 Copa America victory over Bolivia, who became the first team eliminated from the competition.
Bolivia goalkeeper Carlos Lampe scored an unlucky own goal to open the scoring but at times almost single-handedly kept his side in the game.
Paraguay went second in group A behind Argentina with a 2-0 win over Chile, who dropped to third with Uruguay fourth.
The result left Bolivia unable to catch any of the teams above them, who have all qualified for the quarter-finals.