Emma Raducanu became only the third defending champion to exit the US Open in the first round on Tuesday while four-time winner Rafael Nadal overcame an early scare against a player ranked 198 in the world.
Raducanu, 19, slumped to a 6-3, 6-3 defeat to veteran French player Alize Cornet who is competing in a record 63rd consecutive Grand Slam.
Nadal saw off Australian wildcard Rinky Hijikata 4-6, 6-2, 6-3, 6-3 to register his 65th career win in New York.
Also going through to a politically-charged clash were three-time runner-up Victoria Azarenka of Belarus and Marta Kostyuk of Ukraine.
Raducanu has struggled in the spotlight of being a Grand Slam winner, failing to get beyond the second round of any of the previous three majors in 2022.
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