Two women, aged 78 and 90, died while COVID positive between Thursday and Friday, bringing the death toll from the virus to 621.
A total of 301 people meanwhile tested positive for COVID overnight while 87 recovered. New cases topped 300 on Thursday - the first time since January 26.
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This means there are currently 2,073 active cases, 46 of whom are at Mater Dei Hospital.
Of these, one is in ITU.
Health Minister Chris Fearne has attributed a recent rise in cases to a cold snap, increased socialising and the circulation of a subvariant of the Omicron coronavirus strain.